Doctors who treated him said that he passed away peacefully, as reported by Italian outlets.
The Pope reportedly woke up at 6am, fell ill at 7am, and passed away around half-an-hour later.
He alsomet US Vice President JD Vance, marking his highest-profile appearance since being discharged from the hospital.
Pope Francis had a prolonged respiratory crisis that required the administration of high-flow oxygen and transfusions.
He remained hospitalized at Gemelli for 38 days, until March 23, when he was discharged.
He was also diagnosed with a polymicrobial infection and mild renal insufficiency.
May it unite people with each other and with nature.
May this hope continually revive beyond him.
Pope Francis was the rare leader who made us want to be better people.
Pope Francis was the rare leader who made us want to be better people.
This news saddens us deeply, because a great man and a great pastor have left us.
He was a wonderful Pope.
May he rest in peace, one reader wrote